- cooperative 
Venom/Spider-Man: Separation Anxiety is a side-scrolling beat 'em up video game and sequel to Spider-Man and Venom: Maximum Carnage, released for Sega Mega Drive and Super NES and then ported to PC, in which one or two players could team up as Spider ...
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- Single player
Spider-Man and Venom: Maximum Carnage is a side-scrolling beat 'em up game for the Super NES and Sega Genesis/Mega Drive, developed by Software Creations and published by LJN (a subsidiary of Acclaim) in 1994. The game, based on a sprawling comic boo ...
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Fighting Masters (ファイティング マスターズ?) is a Mega Drive/Genesis fighting video game released by Treco in 1991. ...
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- multiplayer
Ultimate Mortal Kombat 3 (UMK3) is a fighting game in the Mortal Kombat series, originally developed and released by Midway Games to arcades in 1995. It is an update of 1995's earlier Mortal Kombat 3 (MK3) with an altered gameplay system, additional ...
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- (except on the Game Boy) multiplayer
Battletoads & Double Dragon is a 1993 beat 'em up developed by Rare and published by Tradewest. It was originally released for the NES and later ported to the Sega Mega Drive/Genesis, Super NES, and Game Boy. ...
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- multiplayer
Boxing Legends of the Ring (known in Japan as ファイナルノックアウト (Final Knockout?)) is a boxing video game for the Mega Drive/Genesis and Super NES consoles. The boxers are represented by 2D sprites see ...
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Mazin Saga: Mutant Fighter (マジンサーガ, known as Mazin Wars in PAL region) is a video game for the Sega Mega Drive. It is a beat em'up/versus fighting game based on the MazinSaga manga by Go Nagai, which was in turn a spin-o ...
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- multiplayer
Streets of Rage 2, released in Japan as Bare Knuckle II: The Requiem of the Deadly Battle (ベア・ナックルII 死闘への鎮魂歌, Bea Nakkuru Tsū: Shitō he no Chinkonka?) and in Europe as Street ...
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- (up to two players[4])
Beast Wrestler (ビースト・ウォリアーズ?, "Beast Warriors") is a 1991 fighting video game that was released exclusively for the Sega Mega Drive in Japan and North America. The game's cover art was created by ...
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- Single player
Eternal Champions is a fighting game originally conceived by Scott Berfield, produced by Mike Latham for Sega of America, and developed by Sega Interactive Development Division in 1993. It was one of the only fighting games of its time developed from ...
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- multiplayer Single player
ClayFighter is a fighting game released for the Super NES in 1994 and later ported to Sega Mega Drive/Genesis in 1994. It was later released on Nintendo's Virtual Console. ...
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- Up to 4 players simultaneously
Captain America and the Avengers (キャプテンアメリカアンドジアベンジャーズ, Kyaputen Amerika ando ji Abenjāzu?) is an arcade game developed and released by Data East i ...
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- Up to 2 players simultaneously
Power Athlete (パワーアスリート?), known outside of Japan for the Sega Mega Drive/Genesis as Deadly Moves or for the Super NES as Power Moves, is a 1992 fighting video game developed by System Vision and published by K ...
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- Up to 2 players simultaneously
Virtua Fighter 2 (Japanese: バーチャファイター2, Hepburn: Bācha Faitā Tsū?) is a fighting game developed by Sega. It is the sequel to Virtua Fighter and the second game in the Virtua Fighter series. It was ...
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- 1st-Person Perspective, 3rd-Person Perspective, Side-Scrolling
Alien Storm (エイリアンストーム?) is a 1990 beat 'em up arcade game by Sega. It was later ported to the Sega Mega Drive/Genesis and Sega Master System. The Sega Mega Drive version was also released on Wii's Virtual ...
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- Single player
Double Dragon II: The Revenge (ダブルドラゴンII ザ・リベンジ, Daburu Doragon II: Za Ribenji?) is a side-scrolling beat 'em up produced by Technōs Japan originally released as a coin-operated arca ...
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